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: Yudkin 1959. McGinn, Colin, ref 1 J. Nisis of New Orleans went even further:Enjoy your press conferences and photo-ops, Mr. Foti. I certainly wont forget this incident the next time youre up for re-election. There was no mention that carbohydrates might be responsible for causing or exacerbating either metabolic syndrome or the combination of low HDL, high triglycerides, and small, dense LDL, which is described as occurringcommonly in persons with premature [coronary heart disease].*53 In the now established version of the alternative hypothesisthat metabolic syndrome leads to heart diseasethe carbohydrates that had always been considered the causative agent had been officially rendered harmless. They had been removed from the equation of nutrition and chronic disease, despite the decades of research and observations suggesting the critical causal role they played.